Endocrine Abstracts

Introduction: There is a great interest in the association of thyroid hormones and mood. Although it appears to be important interactions between the central regulation of mood and the thyroid axis, the effects of antidepressants and especially of selective serotonin reuptake inhibitors (SSRIs) remain ambiguous. We investigated the thyroid function in perimenopausal women suffering from depression.Material and methods: We examined 102 perimenopausal wome...

Introduction: Hot flashes and night sweating are the most common medical complaints in women during the menopausal transition and they are strongly associated with the presence of perimenopausal depression. The pathophysiology of hot flashes has not been elucidated. Peripheral vasodilation and increase in skin temperature observed in women with hot flashes might be induced by changes in brain neurotransmitters and instability in the hypothalamic thermoregulatory center due to ...